IGF1 HGH Peptide Hormones
Long r3 IGF-1 Polypeptide Amino acid bodybuilding peptides used for research. HGH is converted to IGF1 in the liver and is a potent growth factor used by bodybuilders as unique glucose disposal agent.
IGF-1 Long R3 1000mcg - 1mg Vial Recombinant Human Long-Arg3-Insulin-like Growth Factor.
Also known as: IGF1 LR3: Long R3 IGF-1, Insulin-Like Growth Factor, I LR3 & IGF 1. IGF1 mitigates many of the growth promoting effects of growth hormone. Research studies have shown that IGF-1 causes muscle cell hyperplasia, which is a splitting and forming of new muscle cells therefore increasing muscle cell density in lab rats.
IGF-I is a peptide which is approximately the same size and structure as insulin. It is in the peptide family of substances known as growth factors. In the body, IGF-1 is released in the presence of Human Growth Hormone. Although growth hormone is considered to be highly anabolic, in actuality, IGF-1 is suspected to be responsible for the primary muscle growth activities of growth hormone.
IGF-1 promotes nitrogen retention and protein synthesis. This causes the growth of muscles through actual growth of new muscle fibers and an increase in number of muscle cells.
IGF-1 helps the body burn fat at a an elevated rate. It is suspected of increasing neuro function as well. Although IGF-1 is a very powerful muscle builder and fat burner, IGF LR3 is roughly 2-3 times as effective.
Long R3 IGF-1 (Insulin-like Growth Factor -1) is a polypeptide hormone that structurally and molecularly, shares some properties with insulin, which is where it got insulin-like from in its name. IGF-1’s primary roles include long bone growth in children, and in adults igf 1 affects the growth and repair of muscle tissue. Regular IGF1 has a half life of only about 20 minutes, where as the modified version called LR3 is altered some to prevent deactivation by binding proteins in the blood and extends the half life to about 20 hours making it able to be more effective.
IGF-1 LR3 contains the complete IGF-1 sequence, but with the substitution of an Arginine (Arg) for the Glutamic Acid (Glu) at position 3, as well as a 13 amino acid extension peptide is an 83 amino acid analog making the chain 83 aminos in length. This slight change in sequence allows the IGF-1 to avoid binding to proteins and have a much longer half life, around 20-30 hours. This effectively increases the biological activity of the IGF polypeptide. Effects seen in research are increased glucose transport, increased protein synthesis, decreased protein degradation and increased amino acid transport to cells. Active IGF behaves differently in different tissues. In muscle cells proteins and associated cell components are stimulated. Protein synthesis is increased along with amino acid absorption. IGF mobilizes fat for use as energy in adipose tissue. In lean tissue the cells have to switch to burning off fat as a source of energy, as IGF prevents insulin from transporting glucose across cell membranes. IGF-1 promotes nitrogen retention and protein synthesis. This assists the growth of muscles through both hyperplasia (increased number of muscle cells) and mitogenesis (growth of new muscle fibers).